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We assessed synaptic plasticity in isolated striatal synapses using FASS-LTP (Fig

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3 The molecular mechanisms of ferroptosis 3.1 Iron metabolism and ferroptosis Iron homeostasis is maintained by a sophisticated network of absorption, transport, storage, and efflux ( Figure 2 ) ( Figure 2 Ferroportin 1 (Fpn), the sole known mammalian non-heme iron exporter, is widely distributed in neurons, astrocytes, oligodendrocytes, and brain microvascular endothelial cells and is crucial for murine embryonic development, forebrain patterning, and neural tube closure (42, 43)