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10.1016/j.jsxm.2018.05.003 63 MehrsaiA

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312 In addition, apoptosis signal-regulated kinase 1 (ASK1), an upstream activator of the JNK and p38 MAPK signaling cascades, can be activated by stress signals, such as ROS, ER stress, and TNFα, and plays a key role in the progression of NASH 313 (Fig

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