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(2019) performed a randomized controlled trial involving 56 women with PCOS, revealing a decrease in hirsutism, total testosterone, hs-CRP, and MDA, alongside an increase in TAC and total GSH among participants administered 5 g of melatonin twice daily for 12 weeks, in contrast to the placebo group [186]
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EJ bladder cancer cell lines, MCF-7/MDR breast cancer cell lines and 786-O renal cell carcinoma cell lines were purchased from the Cell Culture Center of the Institute of Basic Medicine, Chinese Academy of Medical Sciences (Beijing, China), which were cultured in Dulbecco’s Modified Eagle Medium (DMEM) or Roswell Park Memorial Institute (RPMI) 1640 Medium containing 10% fetal bovine serum, 1% penicillin and streptomycin, 0.1% Mycoplasma Removal Agent at 37 °C in 5% CO 2