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It activates the GIP receptor with approximately equal potency to native GIP, but activates the GLP-1 receptor with roughly five times lower potency than native GLP-1

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Moreover, the experiment infigure 1Bshows that a 3-month treatment with a combination of antioxidants (N-acetylcisteine, vitamin E and lipoic acid), is able to normalize levels of S1P, indicating a previously unreported redox dependence of this pathway in X-ALD