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This early preclinical report demonstrates proof-of-principle that NMDAR antagonists may represent a new class of antidepressants

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However, Bressani further described that lysine-supplemented diets could possess similar nitrogen retention as indicated in milk feedings or in basal wheat diets supplemented to resemble the FAO “reference protein” pattern (in the order of lysine, tryptophan, methionine, isoleucine, valine, and threonine)