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Another study showed that a folate-deficient diet reduced tumor size in a colorectal cancer mouse model with no effect on global or gene-specific DNA methylation

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Expression levels were averaged over technical and biological replicates, Radioactive labeling To quantify the uptake of glycolate, glycine and l-serine ~10,000 synchronized L1 were incubated in liquid cultures as described above and grown for 3 days in the presence of 10 Ci of [1– 14 C]-glycolate, [1– 14 C]-glycine, or L-[1– 14 C]-serine